Multifunctional excipient combining superior flow, compressibility, and disintegration properties
Enhanced flowability due to colloidal silicon dioxide coating, improving powder handling and processing.
Combines the binding properties of MCC with improved compaction characteristics for robust tablets.
Maintains rapid disintegration properties essential for immediate drug release formulations.
Acts as binder, disintegrant, and flow aid simultaneously, simplifying formulation development.
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White to off-white, odorless powder | Visual |
| Identification (MCC) | Complies with USP/EP standards | IR Spectroscopy |
| Identification (Silicon Dioxide) | Complies with USP/EP standards | Chemical Test |
| Silicon Dioxide Content | 1.5 - 2.5% w/w | Gravimetric Analysis |
| pH (1% aqueous slurry) | 5.0 - 7.5 | USP <791> |
| Loss on Drying | ≤ 5.0% | USP <731> |
| Residue on Ignition | ≤ 1.3% | USP <281> |
| Heavy Metals | ≤ 10 ppm | USP <231> |
| Particle Size Distribution | ≥ 95% through 180 μm | USP <786> |
| Bulk Density | 0.25 - 0.35 g/mL | USP <616> |
| Tapped Density | 0.35 - 0.50 g/mL | USP <616> |
| Carr's Index | ≤ 20% | Calculated |
| Microbial Limits | Total Aerobic Count: ≤ 1000 CFU/g Yeast & Mold: ≤ 100 CFU/g |
USP <61> |
Ideal for direct compression tablets with improved flow and compaction properties.
Excellent for IR formulations requiring fast disintegration and drug release.
Superior flow properties make it ideal for capsule filling operations with improved content uniformity.
Provides good mouthfeel and rapid disintegration in chewable formulations.
Fast disintegration properties make it suitable for ODT formulations.
Can be used in wet granulation processes for improved tablet properties.
Our Silicified Microcrystalline Cellulose meets the highest international pharmaceutical standards and regulatory requirements.
United States Pharmacopeia
European Pharmacopoeia
Japanese Pharmacopoeia
Indian Pharmacopoeia
British Pharmacopoeia
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