Advanced pharmaceutical excipient combining Microcrystalline Cellulose and Carboxymethyl Cellulose Sodium for superior tablet performance
.jpeg)
MCC & CMC Sodium (MBC Grades) represents an innovative combination of Microcrystalline Cellulose and Carboxymethyl Cellulose Sodium, specifically designed to provide enhanced functionality in pharmaceutical tablet formulations. This unique blend offers superior binding, disintegration, and flow properties.
Combines MCC and CMC-Na for synergistic effects
Superior tablet hardness and reduced capping
Faster and more uniform tablet disintegration
Enhanced powder flow and content uniformity
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Identification (MCC) | Complies | USP/Ph.Eur |
| Identification (CMC-Na) | Complies | USP/Ph.Eur |
| pH (1% suspension) | 5.0 - 7.5 | Potentiometry |
| Loss on Drying | ≤ 5.0% | USP <105°C, 3h> |
| Residue on Ignition | ≤ 1.3% | USP <800°C> |
| Particle Size (D50) | 50-200 μm | Laser Diffraction |
| Bulk Density | 0.30-0.50 g/cm³ | USP |
| Tapped Density | 0.40-0.65 g/cm³ | USP |
| Heavy Metals | ≤ 10 ppm | USP |
| Lead | ≤ 2 ppm | USP |
| Total Aerobic Count | ≤ 1000 CFU/g | USP |
| Yeast & Mold | ≤ 100 CFU/g | USP |
| E. coli | Absent | USP |
| Salmonella | Absent | USP |
Ideal for direct compression formulations with enhanced flow and compressibility properties.
Excellent performance in wet granulation processes with improved binding characteristics.
Provides rapid disintegration while maintaining tablet integrity and hardness.
Improves powder flow and reduces segregation in capsule filling operations.
Can be used in modified-release formulations for controlled drug delivery.
Suitable for formulations with high active pharmaceutical ingredient content.
Our MBC Grades meet the stringent requirements of major international pharmacopeias
United States Pharmacopeia - National Formulary
European Pharmacopoeia
Japanese Pharmacopoeia
Indian Pharmacopoeia