Carmellose Calcium

Product Overview

Excellent Swelling

Superior swelling capacity in aqueous media for rapid and complete tablet disintegration.

Fast Disintegration

Provides rapid tablet disintegration for immediate drug release and enhanced bioavailability.

Water Insoluble

Insoluble in water but swells rapidly, maintaining structural integrity during disintegration.

Chemical Stability

Excellent chemical stability and compatibility with various active pharmaceutical ingredients.

Quick Info

Chemical Name: Calcium Carboxymethylcellulose
Function: Disintegrant
Appearance: White to off-white powder
Particle Size: Fine powder
Solubility: Insoluble in water, swells rapidly
pH: 6.0 - 8.5 (1% aqueous dispersion)

Compliance

USP EP JP IP

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Technical Specifications

Parameter	Specification	Test Method
Appearance	White to off-white, odorless powder	Visual
Identification	Complies with USP/EP standards	IR Spectroscopy
pH (1% aqueous dispersion)	6.0 - 8.5	USP <791>
Loss on Drying	≤ 10.0%	USP <731>
Residue on Ignition	15.0 - 25.0%	USP <281>
Heavy Metals	≤ 20 ppm	USP <231>
Degree of Substitution	0.6 - 0.95	USP Method
Particle Size Distribution	≥ 95% through 150 μm	USP <786>
Bulk Density	0.3 - 0.7 g/mL	USP <616>
Tapped Density	0.4 - 0.9 g/mL	USP <616>
Swelling Volume	≥ 4.5 mL/g	USP Method
Microbial Limits	Total Aerobic Count: ≤ 1000 CFU/g Yeast & Mold: ≤ 100 CFU/g	USP <61>

Applications

Immediate Release Tablets

Primary application as disintegrant for rapid tablet disintegration and drug release.

Direct Compression

Suitable for direct compression processes with excellent flow and disintegration properties.

Wet Granulation

Compatible with wet granulation processes for improved tablet disintegration.

Chewable Tablets

Enhances disintegration in chewable formulations for improved palatability.

Orally Disintegrating Tablets

Ideal for ODT formulations requiring rapid disintegration in the oral cavity.

Capsule Formulations

Used in capsule formulations to improve drug dissolution and release characteristics.

Regulatory Compliance

Our Carmellose Calcium meets the highest international pharmaceutical standards and regulatory requirements.

USP

United States Pharmacopeia

EP

European Pharmacopoeia

JP

Japanese Pharmacopoeia

IP

Indian Pharmacopoeia

BP

British Pharmacopoeia

Certifications

ISO 9001:2015

Quality Management

ISO 14001:2015

Environmental Management

ISO 45001:2018

Occupational Health & Safety

ISO 22000:2018

Food Safety Management

FSSAI

Food Safety Standards

WHO-GMP

Good Manufacturing Practice

HALAL

Halal Certified

KOSHER

Kosher Certified