Croscarmellose Sodium Cel-Ca-Dissol®

Cellulose Acting as a Catalyst for Dissolution

Modified Sodium Carboxy Methyl Cellulose

Crosslinked Sodium Carboxy Methyl Cellulose

As importance of bio-availability and fast disintegration of pharmaceutical tablet is realised, awarness for super-disintegrants in pharmaceutical tablet formulation is also increasing . Superdisintegrant viz. Sodium Starch Glycollate was also introduced by Maple Biotech Pvt Ltd. in year 1991, which was appreciated in quality and performance by pharmaceutical industry . Although quest for superior quality superdisintegrant was not over . Superdisintegrant with better stability and superior performance at high tablet hardness level was sought and Maple Biotech's R & D department developed the product Crosslinked Sodium Carboxy Methyl Cellulose which is bearing brand name Cel-Ca-Dissol.


PROPERTIES

Cel-Ca-Dissol is white or creamish white in colour and chemically it is cross-linked Sodium Carboxy Methyl Cellulose with very high degree of purity. Very hard tablets where other superdisintegrants do not perform well Cel-Ca-Dissol performs very much satisfactorily. Quantity to be used in pharmaceutical formulation is very less. Cel-Ca-Dissol is required almost half the amount of other brands of Crosslinked Sodium Carboxy Methyl Cellulose to acheive similiar performance of tablet dissolution

ADVANTAGES

  • - good water uptake
  • - high capillary action
  • - rapid swelling properties
  • - efficient fluid channeling compatibility with most actives and excipients
  • - excellent long-term stability
  • - low usage level
  • - low cost-in-use
  • - very fast drug dissolution

Specifications Croscarmellose sodium

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